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NS 101 E, G Doğa ve Bilim I

Sabancı Üniversitesi

Mühendislik ve Doğa Bilimleri Fakültesi

Mekatronik Mühendisliği

Genel Bilgiler

 

Relate the wide range of scales involved in Nature to familiar objects, and explain in his/her own words how we can investigate the module questions using the Scientific method
Recognize Earth as a biosphere, and describe its position and motion in a larger structure such as the Solar system, an environment that hosts a habitable planet
Apply the concept of force and momentum to explain the motions of the planets and what holds the Solar system together, showing all the force vectors correctly
Explain how the solar system may have formed using the concepts of circular motion and angular momentum, and evaluate the uniqueness (or non-) of our solar system based on the formation theory
By providing supporting evidence, describe how molecules of life can be synthesized under conditions similar to those on early Earth
Relate various types of electromagnetic (EM) waves by giving daily-life examples and discuss how we can use the EM waves to search for extraterrestrial life
Discuss the seriousness of the antibiotic resistance problem, interpret parameters of population growth models and calculate bacterial growth
Relate the targets of antibiotics in the bacterial cell and the antibiotic resistance mechanisms to replication, transcription and translation of information encoded in the DNA
Relate the processes of passive (diffusive) and active transport to how drugs move in and out of the bacterial cell
Relate the effect of temperature on the microscopic scale diffusion of antibiotic molecules in bacteria. Model bacterial target molecules using simple shapes and calculate energies for stable conformation of these molecules.
Examine the three-dimensional structures of molecules relevant to the antibiotic resistance problem, classify their bond types and their interactions.
Analyze at atomic scale structures of a given target site and a drug to determine if interactions would be stable, and argue if changes on the binding interface, e.g. due to point mutations, would alter the outcome on the organism scale.
Evaluate the basic physics, chemistry and biology components of antibiotic resistance from an evolutionary biology perspective.

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